Anti-KIF5B Polyclonal Antibody
Cat: K107451P
Summary:
| 【Product name】：Anti-KIF5B Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3799 | 【Swiss Prot】：P33176 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:5000-8000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human KIF5B | |
| 【Public Immunogen Range】：210-260/963aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity). Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity).
Verified picture:
Western blot analysis with KIF5B antibody diluted at 1:6000;Lane: HepG2,Jurkat,A431,293T,HT29,SW480.
Immunohistochemistry of paraffin-embedded Human breast cancer with KIF5B antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human liver cancer with KIF5B antibody diluted at 1:100.