Anti-GADD45A Polyclonal Antibody
Cat: K002991P
Summary:
| 【Product name】：Anti-GADD45A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1647 | 【Swiss Prot】：P24522 |
| 【Species reactivity】：Mouse,Rat,Human | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：A synthetic peptide of human GADD45A | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Verified picture:
Western blot analysis with GADD45A antibody diluted at 1:1000;Lane: HeLa 293T Rat lung.
Immunohistochemistry of paraffin-embedded human liver cancer with GADD45A antibody diluted at 1:100.