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Anti-GADD45A Polyclonal Antibody - SAlexa Fluor 488
Cat: K002991P - SAlexa Fluor 488
Summary:
【Product name】:Anti-GADD45A Polyclonal Antibody - SAlexa Fluor 488 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1647 【Swiss Prot】:P24522
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:FC ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human GADD45A
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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