Anti-CLCN1 Polyclonal Antibody - SAlexa Fluor 594
Cat: K004175P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-CLCN1 Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1180 | 【Swiss Prot】：P35523 |
| 【Species reactivity】：Human,Mouse,Rat | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human CLCN1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.
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