Anti-SRGN Polyclonal Antibody
Cat: K004889P
Summary:
| 【Product name】：Anti-SRGN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5552 | 【Swiss Prot】：P10124 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human SRGN | |
| 【Public Immunogen Range】：28-158aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.
Verified picture:
Western blot analysis with SRGN antibody diluted at 1:1000;Lane:THP-1
Immunohistochemistry of paraffin-embedded human liver damage with SRGN antibody diluted at 1:100