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Anti-AXL Polyclonal Antibody
Cat: K006386P
Summary:
【Product name】:Anti-AXL Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:558 【Swiss Prot】:P30530
【Tested applications】:IP,IF,IHC,WB
【Recommended dilution】:WB 1:500-1000. IHC 1:50-200. IF 1:50-200. IP 0.5μg-4μg.
【Immunogen】:Recombinant protein of human AXL
【Public Immunogen Range】:33-449aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.
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