Anti-TNF alpha Monoclonal Antibody - Biotin
Cat: K009343M - Biotin
Summary:
| 【Product name】：Anti-TNF alpha Monoclonal Antibody - Biotin | 【Source】：Mouse |
| 【Isotype】：IgG1 | |
| 【Gene ID】：7124 | 【Swiss Prot】：P01375 |
| 【Species reactivity】：Rat | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human TNF alpha | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
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