Anti-SFN Polyclonal Antibody
Cat: K107526P
Summary:
| 【Product name】：Anti-SFN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2810 | 【Swiss Prot】：P31947 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-1:3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human SFN | |
| 【Public Immunogen Range】：140-190/248aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
Verified picture:
Western blot analysis with SFN antibody diluted at 1:2000;Lane: HepG2,MCF7.
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with SFN antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human renal cancer with SFN antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human stomach cancer with SFN antibody diluted at 1:100.