Anti-BRMS1 Polyclonal Antibody - SAlexa Fluor 660
Cat: K107530P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-BRMS1 Polyclonal Antibody - SAlexa Fluor 660 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：25855 | 【Swiss Prot】：Q9HCU9 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-1:3000. | |
| 【Immunogen】：A synthetic peptide of human BRMS1 | |
| 【Public Immunogen Range】：196-246/246aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
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