Anti-YWHAQ Polyclonal Antibody
Cat: K107548P
Summary:
| 【Product name】：Anti-YWHAQ Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10971 | 【Swiss Prot】：P27348 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human YWHAQ | |
| 【Public Immunogen Range】：135-185/245aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Verified picture:
Western blot analysis with YWHAQ antibody diluted at 1:2000;Lane: A549,HeLa,A431,NIH/3T3,SW480,HT29,SHSY5Y,Mouse kidney,Mouse brain,Rat brain.
Immunohistochemistry of paraffin-embedded Human ovarian cancer with YWHAQ antibody diluted at 1:200.
Immunohistochemistry of paraffin-embedded Human prostate cancer with YWHAQ antibody diluted at 1:200.
Immunofluorescence analysis of HeLa cells using YWHAQ antibody diluted at 1:100.