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Anti-FGF12 Polyclonal Antibody
Cat: K107570P
Summary:
【Product name】:Anti-FGF12 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:2257 【Swiss Prot】:P61328
【Tested applications】:WB,IF,IHC
【Recommended dilution】:WB 1:1000-1:3000. IHC 1:100-300.IF 1:50-200.
【Immunogen】:A synthetic peptide of human FGF12
【Public Immunogen Range】:10-60/243aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
Verified picture:
Western blot analysis with FGF12 antibody diluted at 1:2000;Lane: 293T.
Immunohistochemistry of paraffin-embedded Rat heart tissue with FGF12 antibody diluted at 1:200.
Immunofluorescence analysis of A431 cells using GNB1 antibody diluted at 1:100.