Anti-PRKN Polyclonal Antibody - Cy5.5
Cat: K107582P - Cy5.5
Summary:
| 【Product name】：Anti-PRKN Polyclonal Antibody - Cy5.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5071 | 【Swiss Prot】：O60260 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human PRKN | |
| 【Public Immunogen Range】：95-145/465aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
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