Anti-GLI-3 Polyclonal Antibody - SAlexa Fluor 568
Cat: K107591P - SAlexa Fluor 568
Summary:
| 【Product name】：Anti-GLI-3 Polyclonal Antibody - SAlexa Fluor 568 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2737 | 【Swiss Prot】：P10071 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB | |
| 【Immunogen】：A synthetic peptide of human GLI-3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
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