Anti-EFNA3 Polyclonal Antibody
Cat: K107608P
Summary:
| 【Product name】：Anti-EFNA3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1944 | 【Swiss Prot】：P52797 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human EFNA3 | |
| 【Public Immunogen Range】：170-220/238aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with EFNA3 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human stomach cancer with EFNA3 antibody diluted at 1:100.