Anti-PPP1R11 Polyclonal Antibody
Cat: K107654P
Summary:
| 【Product name】：Anti-PPP1R11 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：6992 | 【Swiss Prot】：O60927 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human PPP1R11 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901). Inhibitor of protein phosphatase 1 (PubMed:9843442).
Verified picture:
Immunohistochemistry of paraffin-embedded Human liver cancer with PPP1R11 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human lung cancer with PPP1R11 antibody diluted at 1:100.