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Anti-PPP1R11 Polyclonal Antibody - SAlexa Fluor 405
Cat: K107654P - SAlexa Fluor 405
Summary:
【Product name】:Anti-PPP1R11 Polyclonal Antibody - SAlexa Fluor 405 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:6992 【Swiss Prot】:O60927
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC
【Immunogen】:A synthetic peptide of human PPP1R11
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901). Inhibitor of protein phosphatase 1 (PubMed:9843442).
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