Anti-MAN1B1 Polyclonal Antibody
Cat: K107693P
Summary:
| 【Product name】：Anti-MAN1B1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：11253 | 【Swiss Prot】：Q9UKM7 |
| 【Species reactivity】：Mouse | |
| 【Tested applications】：WB | |
| 【Immunogen】：Recombinant protein of human MAN1B1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.
Verified picture:
Western blot analysis with MAN1B1 antibody diluted at 1:2000;Lane: Mouse kidney.