Anti-MAN1B1 Polyclonal Antibody - SAlexa Fluor 532
Cat: K107693P - SAlexa Fluor 532
Summary:
| 【Product name】：Anti-MAN1B1 Polyclonal Antibody - SAlexa Fluor 532 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：11253 | 【Swiss Prot】：Q9UKM7 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-1:3000. | |
| 【Immunogen】：Recombinant protein of human MAN1B1 | |
| 【Public Immunogen Range】：359-698aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.
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