Anti-UMPS Polyclonal Antibody
Cat: K107705P
Summary:
| 【Product name】：Anti-UMPS Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7372 | 【Swiss Prot】：P11172 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：WB,IHC | |
| 【Immunogen】：Recombinant protein of human UMPS | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with UMPS antibody diluted at 1:2000;Lane: HT-29,HeLa,LO2,HepG2,Jurkat,293T,NIH 3T3.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with UMPS antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human stomach cancer with UMPS antibody diluted at 1:100.