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Anti-LPXN Polyclonal Antibody - Biotin
Cat: K107738P - Biotin
Summary:
【Product name】:Anti-LPXN Polyclonal Antibody - Biotin 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9404 【Swiss Prot】:O60711
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human LPXN
【Public Immunogen Range】:1-386aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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