Anti-USP5 Polyclonal Antibody
Cat: K107753P
Summary:
| 【Product name】：Anti-USP5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8078 | 【Swiss Prot】：P45974 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-1:3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human USP5 | |
| 【Public Immunogen Range】：486-835aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).
Verified picture:
Western blot analysis with USP5 antibody diluted at 1:3000;Lane: Mouse brain,Mouse liver,Mouse kidney,Rat brain,A549,NIH/3T3.
Immunohistochemistry of paraffin-embedded Human breast cancer with USP5 antibody diluted at 1:200.