Anti-NPRL2 Polyclonal Antibody - SAlexa Fluor 555
Cat: K107857P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-NPRL2 Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：10641 | 【Swiss Prot】：Q8WTW4 |
| 【Species reactivity】：Human | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human NPRL2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
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