Anti-MRM3 Polyclonal Antibody
Cat: K107861P
Summary:
| 【Product name】：Anti-MRM3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：55178 | 【Swiss Prot】：Q9HC36 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human MRM3 | |
| 【Public Immunogen Range】：1-420aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with MRM3 antibody diluted at 1:2000;Lane: 293T.
Immunohistochemistry of paraffin-embedded Human breast cancer with MRM3 antibody diluted at 1:100.