Anti-TGS1 Polyclonal Antibody - SAlexa Fluor 640
Cat: K107885P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-TGS1 Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：96764 | 【Swiss Prot】：Q96RS0 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC | |
| 【Immunogen】：Recombinant protein of human TGS1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies . Plays a role in transcriptional regulation.
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