Anti-API5 Polyclonal Antibody
Cat: K107949P
Summary:
| 【Product name】：Anti-API5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8539 | 【Swiss Prot】：Q9BZZ5 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:5000-8000. | |
| 【Immunogen】：A synthetic peptide of human API5 | |
| 【Public Immunogen Range】：460-510/524aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Verified picture:
Western blot analysis with API5 antibody diluted at 1:6000;Lane: 293T,K-562,HL-60.