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Anti-NRBF2 Polyclonal Antibody
Cat: K107954P
Summary:
【Product name】:Anti-NRBF2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:29982 【Swiss Prot】:Q96F24
【Tested applications】:WB
【Recommended dilution】:WB 1:1000-3000.
【Immunogen】:A synthetic peptide of human NRBF2
【Public Immunogen Range】:100-150/287aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Involved in starvation-induced autophagy probably by its association with PI3K complex I. However, effects has been described variably. Involved in the induction of starvation-induced autophagy. Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3 . Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1. May be involved in autophagosome biogenesis. May play a role in neural progenitor cell survival during differentiation.
Verified picture:
Western blot analysis with NRBF2 antibody diluted at 1:2000;Lane: A431,A549.