Anti-DIRAS3 Polyclonal Antibody
Cat: K108025P
Summary:
| 【Product name】：Anti-DIRAS3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9077 | 【Swiss Prot】：O95661 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human DIRAS3 | |
| 【Public Immunogen Range】：1-229aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex.
Verified picture:
Western blot analysis with DIRAS3 antibody diluted at 1:2000;Lane: Mouse liver,Mouse kidney,Rat liver.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with DIRAS3 antibody diluted at 1:100.
Immunofluorescence analysis of NIH3T3 cells using DIRAS3 antibody diluted at 1:50.