Anti-MAPK4 Polyclonal Antibody
Cat: K108043P
Summary:
| 【Product name】：Anti-MAPK4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：5596 | 【Swiss Prot】：P31152 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of Human MAPK4 | |
| 【Public Immunogen Range】：415-465/587aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle.
Verified picture:
Immunohistochemistry of paraffin-embedded Human thyroid cancer with MAPK4 antibody diluted at 1:200.