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Anti-NRAS Polyclonal Antibody - SAlexa Fluor 750
Cat: K108051P - SAlexa Fluor 750
Summary:
【Product name】:Anti-NRAS Polyclonal Antibody - SAlexa Fluor 750 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4893 【Swiss Prot】:P01111
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC
【Immunogen】:A synthetic peptide of Human NRAS
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
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