Anti-NRAS Polyclonal Antibody - Cy5
Cat: K108051P - Cy5
Summary:
| 【Product name】：Anti-NRAS Polyclonal Antibody - Cy5 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4893 | 【Swiss Prot】：P01111 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of Human NRAS | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
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