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Anti-SAE1 Polyclonal Antibody
Cat: K108084P
Summary:
【Product name】:Anti-SAE1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:10055 【Swiss Prot】:Q9UBE0
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC
【Immunogen】:A synthetic peptide of Human SAE1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with SAE1 antibody diluted at 1:80.