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Anti-PPM1B Polyclonal Antibody
Cat: K108144P
Summary:
【Product name】:Anti-PPM1B Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5495 【Swiss Prot】:O75688
【Tested applications】:WB;IHC;IF,WB,IF,IHC
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200. IF 1:50-200.
【Immunogen】:Recombinant protein of human PPM1B
【Public Immunogen Range】:1-193aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
Verified picture:
Western blot analysis with PPM1B antibody diluted at 1:2000;Lane: HL-60.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with PPM1B antibody diluted at 1:100.
Immunofluorescence analysis of NIH3T3 cells using PPM1B antibody diluted at 1:100.