Anti-Phospho-MLKL (S358) Polyclonal Antibody - HRP
Cat: K009418P - HRP
Summary:
| 【Product name】：Anti-Phospho-MLKL (S358) Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：197259 | 【Swiss Prot】：Q8NB16 |
| 【Species reactivity】：Human | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human Phospho-MLKL (S358) | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Swiss-Prot Acc.Q8NB16.Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
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