Anti-BMP2 Polyclonal Antibody - Cy3.5
Cat: K108262P - Cy3.5
Summary:
| 【Product name】：Anti-BMP2 Polyclonal Antibody - Cy3.5 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：650 | 【Swiss Prot】：P12643 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB | |
| 【Immunogen】：A synthetic peptide of Human BMP2 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Induces cartilage and bone formation . Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119; which upregulates the expression of ATF4.
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