Anti-BMP2 Polyclonal Antibody - SAlexa Fluor 594
Cat: K108262P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-BMP2 Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：650 | 【Swiss Prot】：P12643 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of Human BMP2 | |
| 【Public Immunogen Range】：250-300/396aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Induces cartilage and bone formation . Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119; which upregulates the expression of ATF4.
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