Anti-ACMSD Polyclonal Antibody - SAlexa Fluor 555
Cat: K108315P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-ACMSD Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：130013 | 【Swiss Prot】：Q8TDX5 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human ACMSD | |
| 【Public Immunogen Range】：1-336aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS
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