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Anti-EIF2S1 Polyclonal Antibody - Cy3
Cat: K108663P - Cy3
Summary:
【Product name】:Anti-EIF2S1 Polyclonal Antibody - Cy3 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1965 【Swiss Prot】:P05198
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of Human EIF2S1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Verified picture: