Anti-FOXO4 Polyclonal Antibody - RBITC
Cat: K108702P - RBITC
Summary:
| 【Product name】：Anti-FOXO4 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4303 | 【Swiss Prot】：P98177 |
| 【Species reactivity】：Human,Mouse | |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of Human FOXO4 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
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