Anti-PKMYT1 Polyclonal Antibody - SAlexa Fluor 405
Cat: K108707P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-PKMYT1 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：9088 | 【Swiss Prot】：Q99640 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB | |
| 【Immunogen】：A synthetic peptide of Human PKMYT1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
Verified picture: