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Anti-MDM4 Polyclonal Antibody
Cat: K108710P
Summary:
【Product name】:Anti-MDM4 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4194 【Swiss Prot】:O15151
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:WB
【Immunogen】:A synthetic peptide of Human MDM4
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Verified picture:
Western blot analysis with MDM4 antibody diluted at 1:2000;Lane: HeLa,MCF7.