Anti-STEAP3 Polyclonal Antibody
Cat: K108713P
Summary:
| 【Product name】：Anti-STEAP3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：55240 | 【Swiss Prot】：Q658P3 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of Human STEAP3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with STEAP3 antibody diluted at 1:80.