Anti-TNF Polyclonal Antibody
Cat: K001653P
Summary:
| 【Product name】：Anti-TNF Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7124 | 【Swiss Prot】：P01375 |
| 【Species reactivity】：Mouse,Human,Rat | |
| 【Tested applications】：IF,IHC,WB | |
| 【Immunogen】：A synthetic peptide of human TNF | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colon with TNF antibody diluted at 1:100
Immunofluorescence analysis of Human breast cancer using TNF antibody diluted at 1:100.
Immunofluorescence analysis of Human mammary cancer cells using TNF antibody diluted at 1:100.