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Anti-CDK9 Polyclonal Antibody
Cat: K002836P
Summary:
【Product name】:Anti-CDK9 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1025 【Swiss Prot】:P50750
【Species reactivity】:Human,Mouse,Rat
【Tested applications】:WB
【Immunogen】:Recombinant protein of human CDK9
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
Verified picture:
Western blot analysis with CDK9 antibody diluted at 1:2000;Lane: HeLa 293T MCF7 NIH3T3.
Immunohistochemistry of paraffin-embedded Human breast cancer with CDK9 antibody diluted at 1:100