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Anti-CD38 Polyclonal Antibody
Cat: K002920P
Summary:
【Product name】:Anti-CD38 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:952 【Swiss Prot】:P28907
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:IF,IHC,WB
【Immunogen】:Recombinant Protein of human CD38
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with CD38 antibody diluted at 1:1000;Lane: Jurkat A549.
Immunohistochemistry of paraffin-embedded human colon carcinoma with CD38 antibody diluted at 1:100.
Immunofluorescence analysis of THP-1 cells using CD38 antibody diluted at 1:100.