下载
Anti-CYP11A1 Polyclonal Antibody
Cat: K002941P
Summary:
【Product name】:Anti-CYP11A1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1583 【Swiss Prot】:P05108
【Species reactivity】:Mouse,Rat,Human
【Tested applications】:IF,IHC,WB
【Immunogen】:Recombinant protein of human CYP11A1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
Verified picture:
Western blot analysis with CYP11A1 antibody diluted at 1:1000;Lane: Mouse testis Mouse ovary Rat testis.
Immunohistochemistry of paraffin-embedded Human colon with CYP11A1 antibody diluted at 1:100
Immunofluorescence analysis of NIH/3T3 using CYP11A1 antibody diluted at 1:100
Immunofluorescence analysis of human placenta using CYP11A1 antibody diluted at 1:30.