Anti-GLRX Polyclonal Antibody
Cat: K003906P
Summary:
| 【Product name】：Anti-GLRX Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：2745 | 【Swiss Prot】：P35754 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：IF,IHC,WB | |
| 【Immunogen】：Recombinant protein of human GLRX | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
Verified picture:
Immunohistochemistry of paraffin-embedded liver cancer(hu) with GLRX antibody diluted at 1:100
Immunofluorescence analysis of C6 cells using GLRX antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded rat spleen with GLRX antibody diluted at 1:100.