Anti-KLKB1 Polyclonal Antibody
Cat: K003908P
Summary:
| 【Product name】：Anti-KLKB1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：3818 | 【Swiss Prot】：P03952 |
| 【Species reactivity】：Rat,Human,Mouse | |
| 【Tested applications】：IHC,WB | |
| 【Immunogen】：Recombinant protein of human KLKB1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with KLKB1 antibody diluted at 1:100
Immunohistochemistry of paraffin-embedded human placenta with KLKB1 antibody diluted at 1:100.