下载
Anti-COMP Polyclonal Antibody - FITC
Cat: K004228P - FITC
Summary:
【Product name】:Anti-COMP Polyclonal Antibody - FITC 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1311 【Swiss Prot】:P49747
【Species reactivity】:Human,Mouse,Rat
【Tested applications】:ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:Recombinant protein of human COMP
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
Verified picture: