Anti-BACE1 Polyclonal Antibody
Cat: K009457P
Summary:
| 【Product name】：Anti-BACE1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：23621 | 【Swiss Prot】：P56817 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：ELISA,IF,ICC,IHC,WB | |
| 【Immunogen】：A synthetic peptide of human BACE1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Verified picture:
Western blot analysis with BACE1 antibody diluted at 1:1000;Lane: SH-SY5Y Huvec.
Immunohistochemistry of paraffin-embedded Mouse pancreas with BACE1 antibody diluted at 1:200
Immunohistochemistry of paraffin-embedded mouse pancreas with BACE1 antibody diluted at 1:200.
Immunofluorescence analysis of Hela cell using BACE1 antibody diluted at 1:100.