Anti-Histone H3/HIST3H3 Polyclonal Antibody - RBITC
Cat: K009469P - RBITC
Summary:
| 【Product name】：Anti-Histone H3/HIST3H3 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8350/8351/8352/8353/8354/8355/8356/8357/8358/8968 | 【Swiss Prot】：P68431 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human Histone H3/HIST3H3 | |
| 【Public Immunogen Range】：71-136/136aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H3 is deposited into chromatin exclusively through a DNA replication-coupled pathway that can be associated with either DNA duplication or DNA repair synthesis during meiotic homologous recombination.
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